The Total Inhibin enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of Total inhibin (Inhibin A, Inhibin B and Inhibin alpha subunit) in human serum, plasma and other biological fluids.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
96 well microtiter
HRP-based ELISA, colorimetric detection by dual wavelength absorbance at 450 nm and 630 nm as reference filter
6, 8.3-525 pg/mL
|Limit of Detection||
Inhibins are heterodimeric protein hormones secreted by granulosa cells of the ovary in the female and Sertoli cells of the testis in the male. They selectively suppress the secretion of pituitary follicle stimulating hormone (FSH) and also have local paracrine actions in the gonads. The fully processed form of the inhibin molecule has a molecular weight of approximately 32 kD and consists of the two distinct chains (α and β), linked by disulfide bridges. Higher molecular weight forms, with precursor forms of the α-subunit, also occur in follicular fluid and serum. In addition, free α-subunit forms, unassociated with a β-subunit, and lacking inhibin bioactivity, are also present. Measurements of Inhibins are shown to be useful in studying its role in human reproductive physiology, spermatogenesis, testicular function, ovarian reserve, granulosa cell tumors and mucinous tumors.
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Total Inhibin ELISA AL-134
Erickson JA, Grenache DG. Performance evaluation of a total inhibin ELISA and reference intervals in female and male populations. Poster session presented at American Association of Clinical Chemistry 2017; July 30-Aug 3, San Diego, CA.
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