The Activin A enzyme linked immunuosorbent assay (ELISA) kit provides materials for the quantitative measurement of Activin A in human serum and other biological fluids. This kit is intended for laboratory research use only and is not for use in diagnostic or therapeutic procedures.
Within United States for Research Use Only. CE Mark kit available for International purchases.
96 well microtiter
HRP-based ELISA, colorimetric detection by dual wavelength absorbance at 450 nm and 630 nm as reference filter
6, 0.1-10 ng/mL
|Limit of Detection||
Activin-A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. The biological activities of Activin-A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, Follistatin. Human Activin-A is a 26 kDa disulfide-linked homodimer of two beta A chains, each containing 116 amino acid residues. Elevated levels of Activin-A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively.
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Activin A ELISA AL-110
Kalra B, Patel A, Kommareddy V, Ganapathy K, Mistry S, Budhavarapu V, Savjani G, Pasternack A, Ritvos O, Hyvonen M, Kumar A. Development of Novel Specific ELISAs for all Inhibins, Activins and their Binding Proteins FST and FSTL3. Poster presented at 98th Annual Endocrine Society Meeting; 2016 Apr 1-3; Boston, MA.
All Products Cited Activin A ELISA AL-110; Inhibin A ELISA AL-123; Inhibin B ELISA AL-107; Activin B ELISA AL-150; Activin AB ELISA AL-153; Follistatin ELISA AL-117; Follistatin Like 3 ELISA AL-152
Kim SY, Ebbert K, Cordeiro MH, Romero MM, Whelan KA, Suarez AA, Woodruff TK, Kurita T. Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors. Cancer Res. 2016 Jul 1;76(13):3851-61. PMID: 27197196
All Products Cited Activin A ELISA AL-110; Inhibin A ELISA AL-123; Inhibin B ELISA AL-107
Skory R, Xu Y, Shea L, Woodruff T. Engineering the ovarian cycle using in vitro follicle culture. Human Reproduction 2015 Mar 16 Epub ahead of print. PMID: 25784584
All Products Cited Activin A ELISA AL-110