| Catalog Number | AB-301-AP031 |
|---|---|
| Packaging | 100 µg |
| Shipping Conditions | This product is shipped on dry ice. Upon receipt, store it immediately at the recommended temperature. |
| Epitopes and Specificity | PAPP -A |
| Source | Murine |
| Product Appearance | Clear, Colorless solution |
| Ab Type | Monoclonal Antibody |
| Isotype | IgG2a |
| Species Reactivity | Human, Mouse |
| Immunogen | Pregnancy Associated Plasma Protein – A (PAPP-A) |
| Purification | Purified from hybridoma culture supernatant using Protein G. |
| Activity | Determined by direct ELISA |
| Composition | Phosphate Buffered Saline, 10mM, pH 7.4 (No Preservatives) |
| Storage | Store at -20°C to -80°C as supplied. Avoid repeated freeze-thaw cycles |
| Availability | Worldwide |
| Regulatory Status | For Research Use Only. Not for use in diagnostic or therapeutic procedures. |
| Application(s) | Neutralizing Ab, WB |
Mikkelsen JH, Resch ZT, Kalra B, Savjani G, Kumar A, Conover CA, Oxvig C. Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity. Oncotarget. 2014; 5:1014–1025.
Heitzeneder S, Sotillo E, Shern JF, Sindiri S, Xu P, Jones R, Pollak M, Noer PR, Lorette J, Fazli L, Alag A, Meltzer P, Lau C, Conover CA, Oxvig C, Sorensen PH, Maris JM, Khan J, Mackall CL. Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion. J Natl Cancer Inst. 2019 Sep 1;111(9):970-982. doi: 10.1093/jnci/djy209.