The picoAMH (Anti-Müllerian hormone) enzyme linked immunuosorbent assay (ELISA) kit provides materials for the quantitative measurement of ultra-low concentrations of AMH in human serum and other biological fluids. This assay is intended for research use only.
Available Research Use Only (AL-124-r) applications.
| Catalog Number(s) | AL-124-r (RUO) |
|---|---|
| Size | 96 well microtiter |
| Price | $950 |
| Analyte | AMH |
| Sample Type | Serum |
| Species Reactivity | Human |
| Sample Size | 10 to 100 uL |
| Dynamic Range | 7.6-1091 pg/ml |
| Limit of Detection | 1.2 pg/mL |
| Assay Time | 4.5 hours |
| Detection | HRP-based ELISA, colorimetric detection by dual wavelength absorbance at 450 nm and 630 nm as reference filter |
| Availability | United States |
| Shelf Life | 24 months |
Anti-Müllerian hormone (AMH), a member of the TGFβ superfamily, is a homodimeric glycoprotein composed of two 55 kDa N-terminal and two 12.5 kDa C-terminal homodimers, non-covalently linked by disulfide bridges.
Recent studies have shown that the AMH C-terminal homodimer is much less active than the noncovalent complex, but almost all activity can be restored by associating with the N-terminal pro-region, which reforms a complex with the mature C-terminal homodimer. This finding raises the possibility that the AMH noncovalent complex is the active form of protein. It was reported that the cleaved AMH noncovalent complex binds to AMHRII and stimulates intracellular signaling, whereas full-length AMH shows only minimal activity.(2)
AMH is secreted by the Sertoli cells in males. During embryonic development, AMH is responsible for Müllerian duct regression. AMH continues to be produced by the testes until puberty and then decreases slowly to residual post-puberty values. In females, AMH is produced by the granulosa cells of small growing follicles from the 36th week of gestation onwards until menopause when levels become undetectable. Potential clinical applications of low end anti-müllerian hormone (AMH) have been published in premature ovarian insufficiency,(3) ovarian tumors,(4-5) menopause(6-8) and many more.
References:
1. Pepinski, R.B., et al. (1988) J. Biol. Chem., 263, 18961-18964.
2. Di Clemente et al. Mol Endocrinol, November 2010, 24 (11): 2193-2206.
3. Méduri G, et. Al.Hum Reprod. 2007;22: 117-23.
4. Lee M, Donahoe et al. Journal of Clinical Endocrinology and Metabolism 1996; 81:571-575.
5. Anderson R.A et al. Human Reproduction 2006, Vol.21 (10): 2583–2592.
6. Robertson, D.M et al. Menopause 2014 Dec; 21(12):1277-1286.
7. Freeman EW, et al. 2012. J Clin Endocrinol Metab;97:1673-1680.
8. Tehrani FR, et al. J Clin Endocrinol Metab 2013; 98:729–735.
9. HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
10. DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 – Explosive Azide Hazard. Available http:// www.cdc.gov/niosh.
11. Approved Guideline – Procedures for the Handling and Processing of Blood Specimens, H18-A3. 2004. Clinical and Laboratory Standards Institute.
AMH (pico) ELISA AL-124
De Kat AC, van der Schouw YT, Eijkemans MJC, Herber-Gast GC, Visser JA, Verschuren WMM, Broekmans FJM. Back to the basics of ovarian aging: a population-based study on longitudinal anti-Müllerian hormone decline. BMC Medicine. 2016;14:151.
All Products Cited: picoAMH ELISA AL-124
Oktay KH, Bedoschi G, Goldfarb SB, Taylan E, Titus S, Palomaki GE, Cigler T, Robson M, Dickler MN. . Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency. Fertil Steril. 2020 Jun;113(6):1251-1260.e1. doi:
10.1016/j.fertnstert.2020.01.033
All Products Cited: AMH (pico) ELISA AL-124
Anderson C, Mark Park YM, Stanczyk FZ, Sandler DP, Nichols HB. Dietary factors and serum Anti-Mullerian hormone concentrations in late premenopausal women. Fertil Steril. 2018 Nov;110(6):1145-1153. doi: 10.1016/j.fertnstert.2018.06.037
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Bertrand KA, Baer HJ, Orav EJ, Klifa C, Kumar A, Hylton NM, LeBlanc ES, Snetselaar LG, Van Horn L, Dorgan JF. Early life body fatness, serum antimüllerian hormone and breast density in young adult women. Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1151-7. doi: 10.1158/1055-9965.EPI-16-0185
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Mamsen LS, Munthe-Fog L, Petersen TS, Jeppesen JV, Møllgård K, Grøndahl ML, Larsen A, Ernst E, Oxvig C, Kumar A, Kalra B, Andersen CY. Reply: Methodological considerations in measuring different AMH splice forms using ELISA: validity of proAMH ELISA. Mol Hum Reprod. 2016 May;22(5):374-5.
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Hawkins Bressler L, Bernardi LA, De Chavez PJ, Baird DD, Carnethon MR, Marsh EE. Alcohol, cigarette smoking, and ovarian reserve in reproductive_age African-American women. Am J Obstet Gynecol. 2016 Dec;215(6):758.e1-758.e9. doi: 10.1016/j.ajog.2016.07.012
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Morse H. Anti-Müllerian hormone as a marker of ovarian reserve in girls before, during and after treatment for childhood cancer. [Dissertation, 2017]. Lund (Sweden): Lund University.
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Bertone-Johnson ER, Manson JE, Purdue-Smithe AC, Hankinson SE, Rosner BA, Whitcomb BW. A prospective study of inflammatory biomarker levels and risk of early menopause. Menopause. 2019 Jan;26(1):32-38. doi: 10.1097/GME.0000000000001162
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Verdiesen RM, van der Schouw YT, van Gils CH, et al. Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women. medRxiv. 2020 Nov 3;2020.10.29.20221390. doi: 10.1101/2020.10.29.20221390
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Purdue-Smithe AC, Whitcomb BW, Manson JE, Hankinson SE, Troy LM, Rosner BA, Bertone-Johnson ER. . Vitamin D Status Is Not Associated with Risk of Early Menopause. J Nutr. 2018 Sep 1;148(9):1445-1452. doi: 10.1093/jn/nxy129
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Mamsen LS, Bøtkjær JA, Kristensen SG, Pors SE, Jeppesen JV, Kumar A, Kalra B, Ernst E, Andersen CY. O-081 High variability of molecular isoforms of AMH in follicular fluid and granulosa cells from human small antral follicles. Front Endocrinol (Lausanne). 2021 Mar 2;12:617523. doi: 10.3389/fendo.2021.617523
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Meczekalski B, Czyzyk A, Kunicki M, Podfigurna-Stopa A, Plociennik L, Jakiel G, Maciejewska-Jeske M, Lukaszuk K. Fertility in women of late reproductive age: the role of serum anti-Müllerian hormone (AMH) levels in its assessment. J Endocrinol Invest. 2016 Nov;39(11):1259-1265.
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Johnson L, Sammel MD, Domchek S, Schanne A, Prewitt M, Gracia C. Antimüllerian hormone levels are lower in BRCA2 mutation carriers. Fertil Steril. 2017 May;107(5):1256-1265.e6.
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Grynnerup G, Løssl K, Pilsgaard F, Lunding S, Storgaard M, Bogstad J, Prætorius L, Zedeler A , Bungum L , Nyboe A, Pinborg A. Prediction of the lower serum anti_Müllerian hormone threshold for ovarian stimulation prior to in-vitro fertilization using the Elecsys AMH assay: a prospective observational study. Grynnerup et al. Reproductive
Biology and Endocrinology (2019) 17:11 https://doi.org/10.1186/s12958-019-0452-4
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Kumar A, Kalra B, Patel A, Shah S, Savjani G, Themmen A, Visser J, Pruysers, Robertson D. Development of Stable picoAnti-Müllerian Hormone ELISA: Sensitive, Reliable and Reproducible Results. Poster session presented at the 96th Annual Endocrine Society Meeting; 2014 Jun 21-24; Chicago, IL.
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Decanter C, Cloquet M, Dassonneville A, D’Orazio E, Mailliez A, Pigny P. Different patterns of ovarian recovery after cancer treatment suggest various individual ovarian susceptibilities to chemotherapy. Reprod Biomed Online. 2018 Jun;36(6):711-718.
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Bertone-Johnson ER, Manson JE, Purdue-Smithe AC, Steiner AZ, Eliassen AH, Hankinson SE, Rosner BA, Whitcomb BW. Anti-Müllerian hormone levels and incidence of early natural menopause in a prospective study. Hum Reprod. 2018 Jun 1;33(6):1175-1182.
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Pilsgaard F, Grynnerup AG, Løssl K, Bungum L, Pinborg A. The use of anti-Müllerian hormone for controlled ovarian stimulation in assisted reproductive technology, fertility assessment and -counseling. Acta Obstet Gynecol Scand. 2018 Feb 24.
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Ge W, Clendenen TV, Afanasyeva Y, Koenig KL, Agnoli C, Brinton LA, Dorgan JF, Eliassen AH, Falk RT, Hallmans G, Hankinson SE, Hoffman-Bolton J, Key TJ, Krogh V, Nichols HB, Sandler DP, Schoemaker MJ, Sluss PM, Sund M, Swerdlow AJ,, Visvanathan K,, Liu M,, Zeleniuch-Jacquotte A. Circulating anti-Müllerian hormone and breast
cancer risk: A study in ten prospective cohorts. Int J Cancer. 2018 Jun 1;142(11):2215-2226.
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Brouwer J, Dolhain RJEM, Hazes JMW, Visser JA, Laven JSE. Reduced Ovarian Function in Female Rheumatoid Arthritis Patients Trying to Conceive. ACR Open Rheumatol 2019 Jul 4;1(5):327-335. doi: 10.1002/acr2.11043. eCollection 2019 Jul.
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Buckbinder J, Mucowski S, Burks H, Stanczyk F, Hodis H, Mack W, Bendikson K, Shoupe D. The Detection and Clinical Utilization of Anti-Mullerian Hormone (AMH) in Postmenopausal Women Using the New Highly Sensitive ELISA. Poster session at American Society for Reproductive Medicine; 2015 Oct 17-21; Baltimore, Maryland
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Saito A, Akira I, Tomoko N, Satoko O, Bayasula, Tomohiko M, Nao K, Chiharu I, Sachiko T, Maki G, Fumitaka K. Involvement of mesosalpinx in endometrioma is a possible risk factor for decrease of ovarian reserve after cystectomy: a retrospective cohort study. Saito et al. Reproductive Biology and Endocrinology (2016) 14:72 DOI
10.1186/s12958-016-0210-9
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Graves JS, Henry RG, Cree BAC, Lambert-Messerlian G, Greenblatt RM, Waubant E, Cedars MI, Zhu A. Ovarian aging is associated with gray matter volume and disability in women with MS. Neurology. 2018 Jan 16;90(3):e254-e260. doi: 10.1212/WNL.0000000000004843
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Ramezani Tehrani F, Sheidaei A, Firouzi F, Tohidi M, Azizi F, Behboudi-Gandevani S. Does the Anti-Mullerian Hormone Decline Rate Improve the Prediction of Age at Menopause?. Front Endocrinol (Lausanne). 2021 Sep 16;12:727229. doi: 10.3389/fendo.2021.727229. eCollection 2021
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Rodriguez-Purata J, Luna M, Cervantes E, Lee J, Whitehouse M, Copperman A, Bandler B. Very Low Levels of Anti-Mullerian Hormone (AMH) in a Large Cohort of ART Patients. Poster session at American Society for Reproductive Medicine; 2015 Oct 17-21; Baltimore, Maryland
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Lukaszuk K, Plociennik L, Lukaszuk A, Dialobrzeska D. The Heterogenity of Anti-Mullerian Hormone Depletion in Models Across Assays in 12917 Women. Poster session at American Society for Reproductive Medicine; 2015 Oct 17-21; Baltimore, Maryland
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Jung S, Allen N, Arslan AA, Baglietto L, Barricarte A, Brinton LA, Egleston BL, Falk RT, Fortner RT, Helzlsouer KJ, Gao Y, Idahl A, Kaaks R, Krogh V, Merritt MA, Lundin E, Onland-Moret NC, Rinaldi S, Schock H, Shu XO, Sluss PM, Staats PN, Sacerdote C, Travis RC, Tjønneland A, Trichopoulou A, Tworoger SS, Visvanathan K, Weiderpass E,
Zeleniuch-Jacquotte A, Dorgan JF. Anti-Müllerian Hormone and risk of ovarian cancer in nine cohorts. Int J Cancer. 2017 Sep 18.
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Ferguson J, Hockley J, Rigsby P, Burns C. Establishment of a WHO Reference Reagent for anti-Mullerian hormone. Ferguson et al. Reproductive Biology and Endocrinology (2020) 18:86 https://doi.org/10.1186/s12958-020-00641-9
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Upson K, Chin HB, Marsh EE, Baird DD. Intrauterine, Infant, and Childhood Factors and Ovarian Reserve in Young African American Women. J Womens Health (Larchmt). 2019 Dec;28(12):1711-1720. doi: 10.1089/jwh.2018.7382
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Lu J, Holt C, Choi M, Kalp K, Straseski J. Quantitation of Anti-Müllerian Hormone by the AnshLabs picoAMH ELISA Assay. Poster session presented at American Association for Clinical Chemistry; 2014 Jul 27-31; Chicago, IL.
All Products Cited: picoAMH ELISA AL-124
Moolhuijsen LME, Visser JA. . Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function. J Clin Endocrinol Metab. 2020 Nov 1;105(11):3361-3373. doi: 10.1210/clinem/dgaa513
All Products Cited: AMH ELISA AL-105; AMH (pico) ELISA AL-124
Brouwer J, Dolhain RJEM, Hazes JMW, Erler NS, Visser JA, Laven JSE. . Decline of ovarian function in patients with rheumatoid arthritis: serum anti_Müllerian hormone levels in a longitudinal cohort. RMD Open. 2020 Oct;6(3):e001307. doi: 10.1136/rmdopen-2020-001307
All Products Cited: AMH (pico) ELISA AL-124
Cameron K, Sammel MD, Prewitt M, Gracia C. Differential Rates of Change in Measures of Ovarian Reserve in Young Cancer Survivors Across the Reproductive Lifespan. J Clin Endocrinol Metab. 2019 May 1;104(5):1813-1822. doi: 10.1210/jc.2018-02257. PMID: 30566616; PMCID: PMC6456010.
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Karlamangla AS. Anti-Mullerian hormone may estimate magnitude of menopausal bone loss. 2016 April 1. Retrieved from http://www.healio.com/endocrinology/bone-mineral-metabolism/news/online/%7B4f8e49d7-e1e8-4567-bdca-dd7d018f7fea%7D/anti-mullerian-hormone-may-estimate-magnitude-of-menopausal-bone-loss .
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Moolhuijsen LME, Louwers YV, McLuskey A, Broer L, Uitterlinden AG, Verdiesen RMG, Sisk RK, Dunaif A, Laven JSE, Visser JA. Association between an AMH promoter polymorphism and serum AMH levels in PCOS patients. Human Reproduction, 2022, deac082, https://doi.org/10.1093/humrep/deac082
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Rivak P, Sachin B. Variation in the Measurement of Anti-Müllerian Hormone – What Are the Laboratory Issues?. Front Endocrinol (Lausanne). 2021 Sep 3;12:719029. doi: 10.3389/fendo.2021.719029
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Chai J, Cameron D, Howie F, Anderson A. A Highly-Sensitive AMH Assay Improves Analysis of Ovarian Function Following Chemotherapy for Early Breast Cancer. European Journal of Cancer 2014 Sep; 50(14):2367-74.
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Robertson DM, Kumar A, Kalra B, Shah S, Pruysers E, Vanden Brink H, Chizen D, Visser JA, Themmen AP, Baerwald A. Detection of serum antimüllerian hormone in women approaching menopause using sensitive antimüllerian hormone enzyme-linked immunosorbent assays. Menopause. 2014 Dec; 21(12):1277-86.
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Ruth KS, Soares ALG, Borges MC, Eliassen AH, Hankinson SE, Jones ME, Kraft P, Nichols HB, Sandler DP, Schoemaker MJ, Taylor JA, Zeleniuch-Jacquotte A, Lawlor DA, Swerdlow AJ, Murray A. Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with
genetic determinants of reproductive lifespan. Hum Mol Genet. 2019 Apr 15;28(8):1392-1401. doi: 10.1093/hmg/ddz015
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Shandley LM, Fothergill A, Spencer JB, Mertens AC, Cottrell HN, Howards PP. Impact of cancer treatment on risk of infertility and diminished ovarian reserve in women with polycystic ovary syndrome. Fertil Steril. 2018 Mar;109(3):516-525.e1.
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Bell RJ, Islam RM, Skiba MA, Herbert D, Martinez Garcia A, Davis SR. Substituting serum anti-Müllerian hormone for polycystic ovary morphology increases the number of women diagnosed with polycystic ovary syndrome: a community-based cross-sectional study. Hum Reprod. 2021 Dec 27;37(1):109-118. doi:
10.1093/humrep/deab232. PMID: 34741176.
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de Kat AC, van der Schouw YT, Eijkemans MJ, Herber-Gast GC, Visser JA, Verschuren WM, Broekmans FJ. Back to the basics of ovarian aging: a population-based study on longitudinal anti-Müllerian hormone decline. BMC Med. 2016 Oct 3;14(1):151.
All Products Cited: picoAMH ELISA AL-124
Iwase A, Nakamura T, Osuka S, Takikawa S, Goto M, Kikkawa F. Anti-Müllerian hormone as a marker of ovarian reserve: What have we learned, and what should we know?. Reprod Med Biol (2016) 15:127–136
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Moolhuijsen LME, Visser JA. Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function. J Clin Endocrinol Metab. 2020 Nov 1;105(11):3361–73. doi: 10.1210/clinem/dgaa513. PMID: 32770239; PMCID: PMC7486884
All Products Cited: AMH ELISA AL-105; picoAMH ELISA AL-124
Su HI, Sammel MD, Homer MV, Bui K, Haunschild C, Stanczyk FZ. Comparability of antimüllerian hormone levels among commercially available immunoassays. Fertility and Sterility. 2014 Jun; 101(6):1766-72.e1.
All Products Cited: AMH ELISA AL-105; picoAMH ELISA AL-124
Straseski J, Lu J, Holt C, Choi M, Kalp K. Analytical Evaluation of the Ansh Labs picoAMH ELISA assay for Anti-Mullerian Hormone. Poster session presented at the 96th Annual Endocrine Society Meeting; 2014 Jun 21-24; Chicago, IL.
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Xu H, Zhang M, Zhang H, Alpadi K, Wang L, Li R, Qiao J. Clinical Applications of Serum Anti-Mullerian Hormone Measurements in Both Males and Females: An Update. Innovation (N Y). 2021 Feb 9;2(1):100091. doi: 10.1016/j.xinn.2021.100091
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Bertrand KA, Eliassen AH, Hankinson SE, Rosner BA, Tamimi RM. Circulating Hormones and Mammographic Density in Premenopausal Women. Horm Cancer. 2018 Apr;9(2):117-127.
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Burks H, Ross L, Opper N, Stancyzk F. Can Ultrasensitive Anti-Mullerian Hormone Testing Predict Failed Response to Ovarian Stimulation? . PCRS Abstracts Vol. 101, No. 2, Supplement, February 2014
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Kopp DM, Wilkinson J, Bengtson A, Chipungu E, Pope RJ, Moyo M, Tang JH. Fertility outcomes following obstetric fistula repair: a prospective cohort study. Kopp et al. Reproductive Health (2017) 14:159 DOI 10.1186/s12978-017-0415-1
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Clendenen TV, Ge W, Koenig KL, Afanasyeva Y, Agnoli C, Brinton LA, Darvishian F, Dorgan JF, Eliassen AH, Falk RT, Hallmans G, Hankinson SE, Hoffman-Bolton J, Key TJ, Krogh V, Nichols HB, Sandler DP, Schoemaker MJ, Sluss PM, Sund M, Swerdlow AJ, Visvanathan K, Zeleniuch-Jacquotte A, Liu M. Breast cancer risk prediction in women
aged 35-50 years: impact of including sex hormone concentrations in the Gail model. Breast Cancer Res. 2019 Mar 19;21(1):42.
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Jung S, Allen N, Arslan AA, Baglietto L, Brinton LA, Egleston BL, Falk R, Fortner RT, Helzlsouer KJ, Idahl A, Kaaks R, Lundin E, Merritt M, Onland-Moret C, Rinaldi S, Sánchez MJ, Sieri S, Schock H, Shu XO, Sluss PM, Staats PN, Travis RC, Tjønneland A, Trichopoulou A, Tworoger S, Visvanathan K, Krogh V, Weiderpass E, Zeleniuch-Jacquotte
A, Zheng W, Dorgan JF. Demographic, lifestyle, and other factors in relation to antimüllerian hormone levels in mostly late premenopausal women. Fertil Steril. 2017 Apr;107(4):1012-1022.e2.
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Welsh P, Smith K, Nelson SM. A single-centre evaluation of two new Anti-Mullerian Hormone assays and comparison with the current clinical standard assay. Human Reproduction. 2014 May; 29(5):1035-41.
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Freeman JR, Whitcomb BW, Roy A, Bertone-Johnson ER, Reich NG, Healy AJ. A pilot longitudinal study of anti-Müllerian hormone levels throughout gestation in low risk pregnancy. Health Sci Rep. 2018 Jun 19;1(8):e53.
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Nichols H, Baird D, Stanczyk F. Anti-Müllerian Hormone Concentrations in Premenopausal Women and Breast Cancer Risk. Cancer Prevention Research. 2015 April 14 epub ahead of print.
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White A, Sandler D, D’Aloisio A, Stanczyk F, Whitworth K, Baird D, Nichols H. Anti-Mullerian hormone (AMH) in relation to tobacco and marijuana use and sources of indoor heating/cooking. Fertility and Sterility. First published online May 27, 2016.
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LambertMesserlian G. The New Egg Timer – AntiMullerian Hormone Levels for Assessing Ovarian Reserve. Clinical Laboratory News. Jan 2015:14-18.
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Burks HR, Ross L, Opper N, Paulson E, Stanczyk F, Chung K. Can highly sensitive antimullerian hormone testing predict failed response to ovarian stimulation? . Fertility and Sterility. 2015 Sep; 104(3):643-648.
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Decanter C, Peigne M, Mailliez A, Morschhauser F, Dassonneville A, Dewailly D, Pigny P. Toward a better follow-up of ovarian recovery in young women after chemotherapy with a hypersensitive antimüllerian hormone assay. Fertility and Sterility. 2014 Aug; 102(2):483-7.
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Robertson DM, Lee CH, Baerwald A. Interactions between serum FSH, inhibin B and antral follicle count in the decline of serum AMH during the menstrual cycle in late reproductive age. Endocrinol Diabetes Metab. 2020 Aug 8;4(2):e00172. doi: 10.1002/edm2.172. PMID: 33855196; PMCID: PMC8029535.
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Marsh EE, Bernardi LA, Steinberg ML, de Chavez PJ, Visser JA, Carnethon MR, Baird DD. Novel correlates between antimullerian hormone and menstrual cycle characteristics in African-American women (23–35 years-old). Fertil Steril. 2016 Apr 23. pii: S0015-0282(16)61100-7. Epub ahead of print.
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Pankhurst MW, Leathart BL, Batchelor NJ, McLennan IS. The Anti-Müllerian Hormone Precursor (proAMH) Is Not Converted to the Receptor-Competent Form (AMHN,C) in the Circulating Blood of Mice. Endocrinology. 2016 Apr;157(4):1622-9. Epub 2016 Feb 1.
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Bungum L, Tagevi J, Jokubkiene L, Bungum M, Giwercman A, Macklon N, Andersen CY, Klausen TW, Torring N, Kumar A, Skouby SO. The Impact of the Biological Variability or Assay Performance on AMH Measurements: A Prospective Cohort Study With AMH Tested on Three Analytical Assay-Platforms. Front. Endocrinol., 16 October
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de Kat AC, van der Schouw YT, Eijkemans MJC, Broer SL, Verschuren WMM, Broekmans FJM. Can menopause prediction be improved with multiple AMH measurements? Results from the prospective Doetinchem Cohort Study. J Clin Endocrinol Metab. 2019 Apr 22. pii: jc.2018-02607.
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Broer SL, Broekmans FJM, Laven JSE, Fauser BCJM. Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications. Hum. Reprod. Update. 2014 May 12.
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Toribio M, Neilan TG, Awadalla M, Stone LA, Rokicki A, Rivard C, Mulligan CP, Cagliero D, Fourman LT, Stanley TL, Ho JE, Triant VA, Burdo TH, Nelson MD, Szczepaniak LS, Zanni MV. Intramyocardial Triglycerides Among Women With vs Without HIV: Hormonal Correlates and Functional Consequences. J Clin Endocrinol Metab. 2019 Dec
1;104(12):6090-6100. doi: 10.1210/jc.2019-01096. PMID: 31393564; PMCID: PMC6954489.
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Kristensen SG, Kumar A, Kalra B, Pors SE, Bøtkjær JA, Mamsen LS, Colmorn LB, Fedder J, Ernst E, Owens LA, Hardy K, Franks S, Andersen CY. Quantitative Differences in TGF-β Family Members Measured in Small Antral Follicle Fluids From Women With or Without PCO. J Clin Endocrinol Metab. 2019 Dec 1;104(12):6371-6384. doi:
10.1210/jc.2019-01094. PMID: 31287539.
All Products Cited: GDF-9 ELISA AL-179; picoAMH ELISA AL-124; Inhibin-A ELISA AL-123; Inhibin-B ELISA AL-107; Inhibin (Total) ELISA AL-134; Activin-A ELISA AL-110; Activin-B ELISA AL-150; Activin AB ELISA AL-153; Follistatin ELISA AL-117; FTSL-3 ELISA AL-152
Finkelstein JS, Lee H, Burnett-Bowie SAM, Santoro N, Yu EW, Joffe H, Morrison A, Kumar A, Greendale GA, Gold E, Harlow S, Lasley BL, Derby C, Randolph JF, Matthews KA, Kravitz HM, McConnell DS, Brooks MM, Martin D, Darakananda K, Hirsch SC, Sluss PM. Utility of Anti-Mullerian Hormone (AMH) for Predicting the Time to the Final
Menstrual Period: The Study of Women’s Health Across the Nation (SWAN). Presented at 98th Annual Endocrine Society Meeting; 2016 Apr 1-3; Boston, MA
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Steiner AZ. AMH as a Predictor of the Final Menstrual Period. J Clin Endocrinol Metab. April 1;105(4):e1908–e1909. https://doi.org/10.1210/clinem/dgaa025
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Huddleston H, Santoro N, Eisenberg E, Haisenleder DJ, Diamond MP, Cedars M. Can We Expect to Improve Age at Menopause Predictions with Repeated AMH Measurements. Poster session at American Society for Reproductive Medicine; 2016 Oct 17-21; Salt Lake City, Utah.
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Cordeiro Mitchell, C.N., McGuinness, B., Fine, E. et al. Navigating the body of literature assessing BRCA1/2 mutations and markers of ovarian function: a systematic review and meta-analysis. Journal of Assisted Reproduction and Genetics volume 37, pages1037–1055 (2020)
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Giuliani E, Waldo A, Bernardi L, Carnethon M, Neff L, Marsh E. Gravidity, Parity, Breastfeeding, and AMH: Findings from the Ovarian Aging and Reserve Study (SOAR). Fertility and Sterility Abstract, Volume 114, Issue 3, Supplement E88, September 01, 2020
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Barad D, Kushnir V, Khanna P, Gleicher N. Clinical in Vitro Fertilization (IVF) Outcomes Based on Comparative Anti-Müllerian Hormone (AMH) Testing with a Standard and New Highly Sensitive Assay. Poster session presented at: Endocrine Society’s 96th Annual Meeting; 2014; June 21-24; Chicago, IL.
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Crawford S, Finkelstein J, Gold E, Greendale G, Harlow S, Joffe H, Kalra B, Kumar A, Martin D, Merillat S, Morrison A, Sluss P, Thurston R, Avis N. Predicting Onset of Menopausal Vasomotor Symptoms with Anti-Mullerian Hormone in the Study of Women’s Health Across the Nation (SWAN). Presented at 98th Annual Endocrine Society
Meeting; 2016 Apr 1-3; Boston, MA
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El Khoudary SR, Wang L, Brooks MM, Matthews KA, Thurston RC, Crawford S, Derby C, Jackson EA, Lee JS, Un-Yong Chae C, McConnell DS, Finkelstein J. Associations of Anti-Mullerian Hormone Premenopausal Levels and Their Changes over the Menopausal Transition with Lipids: The Study of Women′s Health Across the Nation
(SWAN). Presented at 98th Annual Endocrine Society Meeting; 2016 Apr 1-3; Boston, MA
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Finkelstein JS, Lee H, Karlamangla A, Neer RM, Sluss PM, Burnett-Bowie SA, Darakananda K, Donahoe PK, Harlow SD, Prizand SH, Joffe H, Kumar A, Martin DE, McConnell D, Merrilat S, Morrison A, Pastore LM, Randolph JF, Greendale GA, Santoro N. Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study
of Women’s Health Across the Nation. The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 4, April 2020, Pages e1862–e1871, https://doi.org/10.1210/clinem/dgz283
All Products Cited: MenoCheck picoAMH ELISA AL-124; Inhibin B ELISA AL-107
Caanen MR, Peters HE, van de Ven PM, Jüttner AMFM, Laven JSE, van Hooff MHA, Lambalk CB. Anti-Müllerian Hormone Levels in Adolescence in Relation to Long-term Follow-up for Presence of Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1084-e1095. doi: 10.1210/clinem/dgaa949. PMID: 33351079; PMCID:
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Clendenen TV, Ge W, Koenig KL, Afanasyeva Y, Agnoli C, Bertone-Johnson E, Brinton LA, Darvishian F, Dorgan JF, Eliassen AH, Falk RT, Hallmans G, Hankinson SE, Hoffman-Bolton J, Key TJ, Krogh V, Nichols HB, Sandler DP, Schoemaker MJ, Sluss PM, Sund M, Swerdlow AJ, Visvanathan K, Liu M, Zeleniuch-Jacquotte A. Breast Cancer Risk
Factors and Circulating Anti-Müllerian Hormone Concentration in Healthy Premenopausal Women. The Journal of Clinical Endocrinology & Metabolism, Volume 106, Issue 11, November 2021, Pages e4542–e4553
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McLennan IS, Koishi K, Batchelor NJ, Pankhurst MW. Mice with either diminished or elevated levels of anti-Müllerian hormone have decreased litter sizes. Biol Reprod. 2018 Jan 1;98(1):54-62. doi: 10.1093/biolre/iox151. PMID: 29177503.
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Dean A, van den Driesche S, Wang Y, McKinnell C, Macpherson S, Eddie S, Kinnell H, Hurtado-Gonzalez P, Chambers T, Stevenson K, Wolfinger E, Hrabalkova L, Calarrao A, Bayne R, Hagen C, Mitchell R, Anderson R, Sharpe R. Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive
consequences. Sci. Rep. 6, 19789, 2016 Jan 27
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Chai J, Howie F, Cameron DA, Anderson, RA. Analysis of ovarian function following chemotherapy for early breast cancer using an ultra-sensitive assay. Poster session presented at: European Society for Human Reproduction and Embryology; 2014, Jun 29 – July 2 Munich, Germany.
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Iwase A, Osuka S, Nakamura T, Kato N, Takikawa S, Goto M, Kikkawa. Usefulness of the Ultrasensitive Anti-Mullerian Hormone Assay for Predicting True Ovarian Reserve. Reproductive Sciences, 2015, 1-5.
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Verdiesen RMG, Onland-Moret NC, van Gils CH, Stellato RK, Spijkerman AMW, Picavet HSJ, Broekmans FJM, Verschuren WMM, van der Schouw YT. Anti-Müllerian hormone levels and risk of type 2 diabetes in women. Diabetologia. 2021 Feb;64(2):375-384. doi: 10.1007/s00125-020-05302-5. Epub 2020 Oct 13. PMID: 33048171; PMCID:
PMC7801305.
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Shankara-Narayana N, Yu C, Savkovic S, Desai R, Fennell C, Turner L, Jayadev V, Conway AJ, Kockx M, Ridley L, Kritharides L, Handelsman DJ. Rate and Extent of Recovery from Reproductive and Cardiac Dysfunction Due to Androgen Abuse in Men. J Clin Endocrinol Metab. 2020 Jun 1;105(6):dgz324. doi: 10.1210/clinem/dgz324. PMID:
32030409.
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Cui L, Qin Y, Gao X, Lu J, Geng L, Ding L, Qu Z, Zhang X, Chen Z. Anti-Mullerian Hormone: correlation with age and androgenic and metabolic factors in women from birth to postmenopause. Reproductive Endocrinology. 2016 Feb, 105(2):481-5.
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Golenbock SW, Wise LA, Lambert-Messerlian GM, Eklund EE, Harlow BL. Association between a history of depression and anti-müllerian hormone among late-reproductive aged women: the Harvard study of moods and cycles. Womens Midlife Health. 2020 Sep 1;6:9. doi: 10.1186/s40695-020-00056-x. PMID: 32884826; PMCID:
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Whitcomb BW, Purdue-Smithe A, Hankinson SE, Manson JE, Rosner BA, Bertone-Johnson ER. Menstrual Cycle Characteristics in Adolescence and Early Adulthood Are Associated With Risk of Early Natural Menopause. J Clin Endocrinol Metab. 2018 Oct 1;103(10):3909-3918. doi: 10.1210/jc.2018-01110. PMID: 30060103; PMCID:
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Anderson RA, Su HI. The Clinical Value and Interpretation of Anti-Müllerian Hormone in Women With Cancer. Front Endocrinol (Lausanne). 2020 Oct 7;11:574263. doi: 10.3389/fendo.2020.574263. PMID: 33117288; PMCID: PMC7577190.
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Karlamangla AS, Shieh A, Burnett-Bowie SA, Yu EW, Greendale GA, Sluss PM, Martin D, Finkelstein JS. Anti-Mullerian Hormone and Prediction of Trans-Menopausal Bone Loss. Presented at 98th Annual Endocrine Society Meeting; 2016 Apr 1-3; Boston, MA
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Joffe H, Crawford S, Bromberger JT, Kalra B, Kumar A, Morrison A, Finkelstein J, Kravitz JM. Vasomotor Symptoms Mediate the Association Between Anti-Mullerian Hormone Levels and New-Onset Sleep Disturbance in Women during the Menopause Transition: Study of Women’s Health Across the Nation (SWAN). Presented at 98th
Annual Endocrine Society Meeting; 2016 Apr 1-3; Boston, MA
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Sluss PM, Palomaki G, Kumar A, Morrison A, Kalra B, Alpadi K. Analytical Performance and Clinical Value of AMH Testing. J Endocr Soc. 2020 May 8; 4(Suppl 1): SAT-016.Published online 2020 May 8. doi: 10.1210/jendso/bvaa046.1970
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Iliodromiti S, Anderson RA, Nelson SM. Technical and performance characteristics of anti-Müllerian hormone and antral follicle count as biomarkers of ovarian response. Hum Reprod Update. 2015 Nov-Dec;21(6):698-710.
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Iwase A, Nakamura T, Nakahara T, Goto M, Kikkawa F. Anti-Mullerian Hormone and Assessment of Ovarian Reserve After Ovarian Toxic Treatment, a Systematic Narrative Review. Reproductive Sciences. 2015 May, 22(5):519-26.
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